In the United States, as primary means of providing dental care, dental offices are organized as solo practices, group practices, or dental service organizations (DSOs).1 Such entities generally operate in independent fashion. This article reviews and proposes “clique” approach that emphasize the importance of viewing the dentist office as ‘defined node’ of an interconnected ecosystem, rather than an isolated entity, in order to gain a comprehensive understanding of its operations and benefit from “clique”. 2,3,4